She hinted that a "hard" Brexit could see a vote on independence within five years, but insisted that she was offering a "compromise solution" to the British Prime Minister.
Ms Sturgeon has indicated that "soft" Brexit could take the issue of a second referendum on Scottish independence off the table in the short term.
But speaking on BBC One's Andrew Marr Show she said she was prepared to call a fresh vote if the terms of Brexit were not right.
She said "they will be making a big mistake if they think that I'm in any way bluffing" because leaving the European Union created a "fundamental question" for Scotland.
"If we're going to be ignored, if our voice has been completely cast aside, our interests cast aside, then that can happen on anything," she said.
"And we have to ask ourselves in Scotland are we happy to have the direction of our country, the kind of country we want to be determined by a right-wing Conservative government perhaps for the next 20 years, or do we want to take control of our own future.
“And that's the case that in those circumstances I think it would be right for Scotland to have the opportunity to decide."
Asked if she was looking at a referendum "much quicker" than in five or ten years' time if there was a hard Brexit she said: "I would think, yes. But let me not get away from this point, I'm putting to Theresa May a compromise solution.".........http://www.rte.ie/news/2017/0108/843392-scotland-brexit/